Disease: Acidosis, Lactic
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WARS2 Q9UGM6 tryptophanyl tRNA synthetase 2, mitochondrial 5.1E-02 0.617 0.577
TXNIP Q9H3M7 thioredoxin interacting protein 0.16 0.490 0.731
TTR P02766 transthyretin Transporter 0.52 0.423 0.885
TRNL1 tRNA 0.534 0.731
TPK1 Q9H3S4 thiamin pyrophosphokinase 1 Kinase 9.1E-02 0.792 0.269
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TFAM Q00059 transcription factor A, mitochondrial 0.17 0.529 0.731
SURF1 Q15526 SURF1 cytochrome c oxidase assembly factor Enzyme 1.6E-13 0.578 0.654
SUCLA2 Q9P2R7 succinate-CoA ligase ADP-forming subunit beta Enzyme 2.3E-03 0.566 0.654
SRSF2 Q01130 serine and arginine rich splicing factor 2 Nucleic acid binding 0.48 0.561 0.731
SLC5A2 P31639 solute carrier family 5 member 2 Transporter 4.9E-14 0.499 0.769
SLC47A1 Q96FL8 solute carrier family 47 member 1 Transporter 2.0E-14 0.729 0.462
SLC25A4 P12235 solute carrier family 25 member 4 Transporter 0.45 0.568 0.692
SI P14410 sucrase-isomaltase Enzyme 3.9E-60 0.569 0.692
PTGS1 P23219 prostaglandin-endoperoxide synthase 1 Enzyme 6.2E-07 0.460 0.885
PTBP1 P26599 polypyrimidine tract binding protein 1 1.00 0.517 0.769
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
PLAT P00750 plasminogen activator, tissue type Enzyme 5.7E-05 0.445 0.885
PDP1 Q9P0J1 pyruvate dehyrogenase phosphatase catalytic subunit 1 Enzyme 0.45 0.691 0.462
PCK1 P35558 phosphoenolpyruvate carboxykinase 1 Kinase 8.7E-15 0.608 0.538
PC P11498 pyruvate carboxylase Enzyme 1.4E-02 0.515 0.808
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846
NUBPL Q8TB37 nucleotide binding protein like 1.1E-05 0.670 0.423
NDUFAF6 Q330K2 NADH:ubiquinone oxidoreductase complex assembly factor 6 9.1E-08 0.659 0.615
NDUFA6 P56556 NADH:ubiquinone oxidoreductase subunit A6 Enzyme 1.3E-04 0.711 0.346